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Functional analysis of the GPAT4 gene mutation predicted to affect splicing.

Animal biotechnology - 1 Nov 2024

Bursakov Sergey A, Kovaleva Anastasia V, Brigida Artyom V, Zaripov Oleg G

Abstract excerpt

The GPAT4 gene is considered as a potential functional candidate for single nucleotide polymorphism (SNP) studies in dairy cattle breeding due to its association with dairy performance in cattle by encoding an enzyme responsible for the presence of diacylglycerols and triacylglycerols in milk. Using the example of the GPAT4 gene, we applied the minigene splicing assay to analyze the functional consequences of its...

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PMID: 37906284
DOI: 10.1080/10495398.2023.2269210

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