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The Relationship Between Efficacy and Safety of Osimertinib Blood Concentration in Patients With EGFR Mutation-positive Lung Cancer: A Prospective Observational Study.

In vivo (Athens, Greece) - 1 Jan 2000

Hashino Yasuhisa, Hatsuyama Tae, Iwayama Kuninori, Hoshi Takanobu, Wakamoto Azusa, Ohtaki Koichi, Toda Takaki, Sato Hideki

Abstract excerpt

BACKGROUND/AIM: Osimertinib blood levels and their impact on treatment continuation in patients with EGFR mutation-positive lung cancer is not known. This study investigated the drug blood levels and risk factors affecting treatment continuation. PATIENTS AND METHODS: Fifty-six patients with recurrent and inoperable epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer who received...

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Carcinoma, Non-Small-Cell Lung
ErbB Receptors
Lung Neoplasms
Mutation
Protein Kinase Inhibitors

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PMID: 37905656
DOI: 10.21873/invivo.13376
PMCID: PMC10621464

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