Article
[An emerging problem: heteroresistance in Mycobacterium tuberculosis].
Medicina - 1 Jan 2023
Gamberale Ana, Bartoletti Bruno, Cruz Víctor, Matteo Mario, Latini Cecilia, Paul Roxana, Lorenzo Federico, Símboli Norberto, Palmero Domingo
Abstract excerpt
Mixed infection by Mycobacterium tuberculosis (Mtb) consists in the simultaneous coexistence in the same patient of two different strains of Mtb or 2 different variants of the same strain. When one of the variants selects for resistance mutations, it is called monoclonal heteroresistance (HTR); if there are 2 different strains, one sensitive and one resistant (or with different resistance patterns), it is called...
Topics
- Humans
- Mycobacterium tuberculosis
- Tuberculosis, Multidrug-Resistant
- Acquired Immunodeficiency Syndrome
- Mutation
- Antitubercular Agents
