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Article

Incorporating mutations and bone marrow fibrosis into the revised international prognostic scoring system in myelodysplastic syndromes.

Leukemia & lymphoma - 1 Jan 2024

Zhao Youshan, Guo Juan, Zhao Sida, Wang Roujia, Wu Dong, Chang Chunkang

Abstract excerpt

The independent prognostic significance of bone marrow fibrosis (BMF) in myelodysplastic syndromes (MDS) is challenged under currently molecular prognostic models. In this study, the clinical and genetic data from 438 MDS patients were analyzed retrospectively. The patients were randomly divided into training (n = 306) and validation (n = 132) cohorts. The independent significant prognostic factors included age,...

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Source

Identifiers

PMID: 37865969
DOI: 10.1080/10428194.2023.2271593

Genes

BMF
TP53
U2AF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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