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Article

Acute Myeloid Leukemia Arising from Myelodysplastic Syndromes.

Clinics in laboratory medicine - 1 Dec 2023

Kwon Adelaide, Weinberg Olga K

Abstract excerpt

Myelodysplastic syndromes (MDS) are a group of myeloid neoplasms characterized by clonal hematopoiesis and abnormal maturation of hematopoietic cells, resulting in cytopenias. The transformation of MDS to acute myeloid leukemia (AML) reflects a progressive increase in blasts due to impaired maturation of the malignant clone, and thus MDS and many AML subtypes form a biological continuum rather than representing...

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PMID: 37865509
DOI: 10.1016/j.cll.2023.07.001

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