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Article

Scalable and interpretable alternative to chart review for phenotype evaluation using standardized structured data from electronic health records.

Journal of the American Medical Informatics Association : JAMIA - 22 Dec 2023

Ostropolets Anna, Hripcsak George, Husain Syed A, Richter Lauren R, Spotnitz Matthew, Elhussein Ahmed, Ryan Patrick B

Abstract excerpt

OBJECTIVES: Chart review as the current gold standard for phenotype evaluation cannot support observational research on electronic health records and claims data sources at scale. We aimed to evaluate the ability of structured data to support efficient and interpretable phenotype evaluation as an alternative to chart review. MATERIALS AND METHODS: We developed Knowledge-Enhanced Electronic Profile Review (KEEPER)...

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PMID: 37847668
DOI: 10.1093/jamia/ocad202
PMCID: PMC10746303

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