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Gefitinib, an effective treatment option for patients with pulmonary enteric adenocarcinoma harboring compound EGFR L858R and A871G mutation.

Investigational new drugs - 1 Dec 2023

Cui Yujie, Liang Jinlong, Kang Xiyun, Liu Miaomiao, Zhang Qi, Zhang Hongzhen

Abstract excerpt

Pulmonary enteric adenocarcinoma (PEAC) is a rare lung adenocarcinoma with morphological and immunohistochemical similarities to colorectal adenocarcinoma and intestinal differentiation. PEAC belongs to the group of non-small-cell lung carcinoma (NSCLC) and is defined as having a more than 50% intestinal differentiation component. We report a postoperative (T4N2M0 stage IIIb) PEAC patient with EGFR L858R + A871G...

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PMID: 37831287
DOI: 10.1007/s10637-023-01401-3

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