Article
Fibrinogen Aα gene genotyping in patients with inherited afibrinogenemia deficiency; a novel mutation in Iranian afibrinogenemia patients.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Dec 2023
Moazzeni Ali, Naderi Majid, Dorgalaleh Akbar, Alizadeh Shaban
Abstract excerpt
BACKGROUND: Congenital fibrinogen deficiencies (CFD) are a group of rare bleeding disorders (RBD). Afibrinogenemia as a subclass of these disorders would occurs as a result of mutations in fibrinogen gene. Here in, the sequences of Aα chain of fibrinogen (FGA) in patients with inherited afibrinogenemia disorder in south-eastern of Iran were analysed. METHODS: The FGA gene exons were amplified using PCR method and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.