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Airway surveillance and lung viral control by memory T cells induced by COVID-19 mRNA vaccine

5 Oct 2023

Abstract excerpt

Although SARS-CoV-2 evolution seeds a continuous stream of antibody-evasive viral variants, COVID-19 mRNA vaccines provide robust protection against severe disease and hospitalization. Here, we asked whether mRNA vaccine-induced memory T cells limit lung SARS-CoV-2 replication and severe disease. We show that mice and humans receiving booster BioNTech mRNA vaccine developed potent CD8 T cell responses and showed...

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Share to Immune Cell Function and Interaction
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PMID: 37796612
DOI: 10.1172/jci.insight.172510

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