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Innate immune response restarts adaptive immune response in tumors

14 Sept 2023

Abstract excerpt

The imbalance of immune response plays a crucial role in the development of diseases, including glioblastoma. It is essential to comprehend how the innate immune system detects tumors and pathogens. Endosomal and cytoplasmic sensors can identify diverse cancer cell antigens, triggering the production of type I interferon and pro-inflammatory cytokines. This, in turn, stimulates interferon stimulating genes,...

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PMID: 37781382
DOI: 10.3389/fimmu.2023.1260705

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