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Is Cell-Free DNA Testing in Hepatocellular Carcinoma Ready for Prime Time?

International journal of molecular sciences - 18 Sept 2023

Jeepalyam Sravan, Sheel Ankur, Ejaz Aslam, Miller Eric, Manne Ashish

Abstract excerpt

Revamping the current biomarker landscape of hepatocellular carcinoma (HCC) with cell-free DNA (cfDNA) could improve overall outcomes. The use of commercially available cfDNA testing (also known as liquid biopsy) is limited by the low prevalence of targetable mutations and does not have any prognostic or predictive value. Thus, current cfDNA testing cannot be relied upon for perioperative risk stratification...

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Identifiers

PMID: 37762533
DOI: 10.3390/ijms241814231
PMCID: PMC10531802

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