TP53 mutation and abnormal p53 expression in endometrial cancer: Associations with race and outcomes.

doi:10.1016/j.ygyno.2023.09.009

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Article

TP53 mutation and abnormal p53 expression in endometrial cancer: Associations with race and outcomes.

Gynecologic oncology - 1 Nov 2023

Whelan Karley, Dillon Mairead, Strickland Kyle C, Pothuri Bhavana, Bae-Jump Victoria, Borden Lindsay E, Thaker Premal H, Haight Paulina, Arend Rebecca C, Ko Emily, Jackson Amanda L, Corr Bradley R, Ayoola-Adeola Martins, Wright Jason D, Podwika Sarah, Smitherman Carson, Thomas Samantha, Lightfoot Michelle, Newton Meredith, Washington Christina, Mullen Mary, Cosgrove Casey, Harsono Alfonsus Adrian Hadikusumo, Powell Kristina, Herzog Thomas J, Salani Ritu, Alvarez Secord Angeles

Abstract excerpt

OBJECTIVE: This multi-center cohort study assessed associations between race, TP53 mutations, p53 expression, and histology to investigate racial survival disparities in endometrial cancer (EC). METHODS: Black and White patients with advanced or recurrent EC with Next Generation Sequencing data in the Endometrial Cancer Molecularly Targeted Therapy Consortium database were identified. Clinicopathologic and...

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PMID: 37748270
DOI: 10.1016/j.ygyno.2023.09.009

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