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Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection

25 Sept 2023

Abstract excerpt

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. While a close correlation between chronic Helicobacter pylori infection and CRC has been reported, the role of the virome has been overlooked. Here, we infected Apc-mutant mouse models and C57BL/6 mice with H. pylori and conducted a comprehensive metagenomics analysis of H. pylori-induced changes in lower gastrointestinal tract...

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PMID: 37747149
DOI: 10.1080/19490976.2023.2257291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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