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Metagenomic analysis of primary colorectal carcinomas and their metastases identifies potential microbial risk factors

30 Jul 2021

Abstract excerpt

The paucity of microbiome studies at intestinal tissues has contributed to a yet limited understanding of potential viral and bacterial cofactors of colorectal cancer (CRC) carcinogenesis or progression. We analysed whole-genome sequences of CRC primary tumours, their corresponding metastases and matched normal tissue for sequences of viral, phage and bacterial species. Bacteriome analysis showed Fusobacterium...

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PMID: 34328665
DOI: 10.1002/1878-0261.13070

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