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Article

[Effect of spatial coupling of amino acid residues on the possibility of mutational substitution in globular proteins].

Molekuliarnaia biologiia - 1 Jan 2000

Lukashev V A, Bachinskiĭ A G, Kulichkov V A

Abstract excerpt

Amino acid residues can be divided into similar groups by frequencies of interreplacements in the evolutionary pathway and by trends to spatial contacts at the tertiary structures of globular proteins. Each residue was compared to the cluster of spatial surrounding--the totality of residues spacially drawn together. 5210 clusters in 32 unhomologous proteins with established tertiary structure and 6447 clusters...

Topics

Amino Acid Sequence
Mutation
Protein Conformation
Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 3773887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3773887-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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