Successful cord blood transplantation for del7q myelodysplastic syndrome in Pearson marrow pancreas syndrome

Abstract excerpt

Pearson marrow pancreas syndrome (PS) is a multisystem bone marrow failure (BMF) disorder caused by deletions in mitochondrial DNA (mtDNA). Infant-onset transfusion-dependent pancytopenia, immune defects, and metabolic crises result in early mortality. However, PS often goes undiagnosed, and its rarity, comorbidities, and occasional spontaneous hematologic improvement deter timely consideration of hematopoietic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Acute Myeloid Leukemia Research
• Share to Metabolism and Genetic Disorders
• Share to Mitochondrial Function and Pathology