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Identification of metabolism-related subtypes and feature genes in Alzheimer’s disease

15 Sept 2023

Abstract excerpt

BACKGROUND: Owing to the heterogeneity of Alzheimer's disease (AD), its pathogenic mechanisms are yet to be fully elucidated. Evidence suggests an important role of metabolism in the pathophysiology of AD. Herein, we identified the metabolism-related AD subtypes and feature genes. METHODS: The AD datasets were obtained from the Gene Expression Omnibus database and the metabolism-relevant genes were downloaded...

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PMID: 37715200
DOI: 10.1186/s12967-023-04324-y

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