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Recent Advances in Understanding the Human Fungal Pathogen Hypoxia Response in Disease Progression

15 Sept 2023

Abstract excerpt

Fungal-mediated disease progression and antifungal drug efficacy are significantly impacted by the dynamic infection microenvironment. At the site of infection, oxygen often becomes limiting and induces a hypoxia response in both the fungal pathogen and host cells. The fungal hypoxia response impacts several important aspects of fungal biology that contribute to pathogenesis, virulence, antifungal drug...

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PMID: 37713457
DOI: 10.1146/annurev-micro-032521-021745

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