Article
Differences in mutational signature of diffuse large B-cell lymphomas according to the primary organ.
Cancer medicine - 1 Oct 2023
Koh Hyun-Hee, Yoon Sang Eun, Kim Seok Jin, Kim Won Seog, Cho Junhun
Abstract excerpt
BACKGROUND: Comprehensive molecular subtyping of diffuse large B-cell lymphoma (DLBCL) through genetic profiling has broadened our understanding of DLBCL biology. In this study, we investigated whether DLBCL, not otherwise specified (NOS) shows differences in mutational patterns depending on the primary organ. PATIENTS AND METHODS: Panel-based next-generation sequencing was performed on 345 DLBCL from various...
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