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Combined analysis of 16S rDNA sequencing and metabolomics to find biomarkers of drug-induced liver injury

13 Sept 2023

Abstract excerpt

Drug induced liver injury (DILI) is a kind of liver dysfunction which caused by drugs, and gut microbiota could affect liver injury. However, the relationship between gut microbiota and its metabolites in DILI patients is not clear. The total gut microbiota DNA was extracted from 28 DILI patient and 28 healthy control volunteers (HC) and 16S rDNA gene were amplified. Next, differentially metabolites were...

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PMID: 37704684
DOI: 10.1038/s41598-023-42312-w

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