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Article

Lazertinib Versus Gefitinib Tyrosine Kinase Inhibitors in Treatment-Naíve Patients With EGFR-Mutated Advanced NSCLC: Analysis of the Asian Subpopulation in LASER301.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2023

Reungwetwattana Thanyanan, Cho Byoung Chul, Lee Ki Hyeong, Pang Yong Kek, Fong Chin Heng, Kang Jin Hyoung, Lee Yun-Gyoo, Lim Chun Sen, Danchaivijitr Pongwut, Lim Yueh Ni, Lee Youngjoo, How Soon Hin, Geater Sarayut, Lee Sung Sook, Min Young Joo, Kim Joo-Hang, Lee Jong-Seok, Lee Gyeong-Won, Soo Ross A, Lee Sae Young, Choi SeokYoung, Ahn Myung-Ju

Abstract excerpt

INTRODUCTION: Lazertinib is a third-generation central nervous system-penetrant tyrosine kinase inhibitor targeting mutant EGFR in NSCLC. Lazertinib exhibited improved efficacy versus gefitinib in the LASER301 study; this subset analysis compared lazertinib with gefitinib among Asian patients. METHODS: The phase 3 LASER301 study evaluated lazertinib efficacy and safety in treatment-naive patients with...

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Identifiers

PMID: 37702629
DOI: 10.1016/j.jtho.2023.06.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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