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Intratumour microbiota modulates adrenocortical cancer responsiveness to mitotane

21 Aug 2023

Abstract excerpt

The infiltrating microbiota represents a novel cellular component of the solid tumour microenvironment that can influence tumour progression and response to therapy. Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy for which mitotane (MTT) treatment represents the first-line therapy, though its efficacy is limited to a therapeutic window level (14-20 mg/L). Novel markers able to...

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Share to Adrenal and Paraganglionic Tumors
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PMID: 37695690
DOI: 10.1530/erc-23-0094

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