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Molecular characteristics and therapeutic implications of Toll-like receptor signaling pathway in melanoma

4 Sept 2023

Abstract excerpt

Melanoma is a malignant tumor of melanocytes and is often considered immunogenic cancer. Toll-like receptor-related genes are expressed differently in most types of cancer, depending on the immune microenvironment inside cancer, and the key function of Toll-like receptors (TLRs) for melanoma has not been fully elucidated. Based on multi-omics data from TCGA and GEO databases, we first performed pan-cancer...

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PMID: 37666853
DOI: 10.1038/s41598-023-38850-y

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