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Article

Genome analysis of SARS-CoV-2 isolates from a population reveals the rapid selective sweep of a haplotype carrying many pre-existing and new mutations.

Virology journal - 1 Sept 2023

Bhattacharjee Maloyjo Joyraj, Bhattacharya Anupam, Kashyap Bhaswati, Taw Manash Jyoti, Li Wen-Hsiung, Mukherjee Ashis K, Khan Mojibur Rohman

Abstract excerpt

To understand the mechanism underlying the evolution of SARS-CoV-2 in a population, we sequenced 92 viral genomes from Assam, India. Analysis of these and database sequences revealed a complete selective sweep of a haplotype in Assam carrying 13 pre-existing variants, including a high leap in frequency of a variant on ORF8, which is involved in immune evasion. A comparative study between sequences of same lineage...

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Identifiers

PMID: 37658381
DOI: 10.1186/s12985-023-02139-3
PMCID: PMC10474745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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