Article
TP53 status and impact on AML prognosis within the ELN 2022 risk classification.
Blood - 7 Dec 2023
Fleming Shaun, Tsai Xavier Cheng-Hong, Morris Rhiannon, Hou Hsin-An, Wei Andrew H
Abstract excerpt
This study reports the following: (1) frequency of TP53 comutation within each component of the European LeukemiaNet 2022 acute myeloid leukemia risk classification, (2) relevance of TP53 mutated variant allelic fraction <10%, (3) prognostic impact of -7, -5/del(5q), -17/abn(17p), complex karyotype/monosomal karyotype, or myelodysplasia-related gene mutations with/without mutated TP53.
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