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Identification of novel tumor-associated antigens and evaluation of a panel of autoantibodies in detecting oral cancer

28 Aug 2023

Abstract excerpt

BACKGROUND: We aimed to identify tumor-associated antigen (TAA) biomarkers through bioinformatic analysis and experimental verification, and to evaluate a panel of autoantibodies against tumor-associated antigens (TAAbs) for the detection of oral cancer (OC). METHODS: GEO and TCGA databases were used to screen significantly up-regulated genes related to OC, and protein-protein interaction (PPI) analysis and...

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PMID: 37641028
DOI: 10.1186/s12885-023-11247-w

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