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Unraveling the transcriptome-based network of tfh cells in primary sjogren syndrome: insights from a systems biology approach

10 Aug 2023

Abstract excerpt

Background: Primary Sjogren Syndrome (pSS) is an autoimmune disease characterized by immune cell infiltration. While the presence of follicular T helper (Tfh) cells in the glandular microenvironment has been observed, their biological functions and clinical significance remain poorly understood. Methods: We enrolled a total of 106 patients with pSS and 46 patients without pSS for this study. Clinical data and...

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PMID: 37638029
DOI: 10.3389/fimmu.2023.1216379

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