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Article

Preliminary exploration of the effects of environmental factors on the microsatellite status of BRAF-mutated colorectal cancer.

World journal of surgical oncology - 25 Aug 2023

Tian Binle, Chen Guiming, Shi Xiaoqin, Jiang Liren, Jiang Tao, Li Qi, Yuan Lin, Qin Jian

Abstract excerpt

BACKGROUND: To investigate the expression of EBV products and frequency of gallstone disease (GD) among different microsatellite status in colorectal cancer (CRC) with BRAFV600E mutation. METHODS: We collected 30 CRC patients with BRAFV600E mutation and 10 BRAF ( -) CRC patients as well as 54 healthy subjects. Tumor tissue samples were collected to detect the mutation of BRAF, KRAS, and TP53. Microsatellite...

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Identifiers

PMID: 37620872
DOI: 10.1186/s12957-023-03106-6
PMCID: PMC10463889

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