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Emerging and potential use of CRISPR in human liver disease

23 Aug 2023

Abstract excerpt

CRISPR is a gene editing tool adapted from naturally occurring defense systems from bacteria. It is a technology that is revolutionizing the interrogation of gene functions in driving liver disease, especially through genetic screens and by facilitating animal knockout and knockin models. It is being used in models of liver disease to identify which genes are critical for liver pathology, especially in genetic...

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PMID: 37607734
DOI: 10.1097/hep.0000000000000578

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