The gut microbiome contributes to somatic morphine withdrawal behavior and implicates a TLR2 mediated mechanism

Abstract excerpt

The ongoing opioid epidemic has left millions of people suffering from opioid use disorder due to the over-prescription of highly addictive substances. Chronic opioid exposure leads to dependence, where the absence of the drug results in negative symptoms of withdrawal, often driving patients to continue drug use; however, few therapeutic strategies are currently available to combat the cycle of addiction and the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diet and metabolism studies
• Share to Gut microbiota and health
• Share to Tryptophan and brain disorders