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Integrated proteomics and genomics analysis of paradoxical eczema in psoriasis patients treated with biologics

1 Aug 2023

Abstract excerpt

BACKGROUND: Few studies have explored the immunology and genetic risk of paradoxical eczema occurring as an adverse event of biologic therapy in patients with psoriasis. OBJECTIVES: We sought to describe the systemic inflammatory signature of paradoxical eczema using proteomics and explore whether this is genetically mediated. METHODS: This study used the Olink Target 96 Inflammation panel on 256 serum samples...

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PMID: 37536512
DOI: 10.1016/j.jaci.2023.07.011

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