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Article

Noonan syndrome: rhGH treatment and PTPN11 mutation.

Molecular genetics & genomic medicine - 1 Nov 2023

Wu Xian, Wu Jiali, Yuan Yi, Yang Li, Yu Lirong

Abstract excerpt

OBJECTIVE: To analyze the clinical data and genetic characteristics of Noonan syndrome, both the effect and side effects of recombinant human growth hormone (rhGH) treatment. METHODS: We collected clinical data from 8 children with Noonan syndrome diagnosed from November 2017 to June 2021. The diagnosis was clarified by exome second-generation sequencing and parental PCR-NGS validation and interpretation of the...

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Identifiers

PMID: 37525886
DOI: 10.1002/mgg3.2266
PMCID: PMC10655517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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