Article
Obese Asthma Phenotype Is Associated with hsa-miR-26a-1-3p and hsa-miR-376a-3p Modulating the IGF Axis.
International journal of molecular sciences - 18 Jul 2023
Gil-Martínez Marta, Lorente-Sorolla Clara, Rodrigo-Muñoz José M, Naharro Sara, García-de Castro Zahara, Sastre Joaquín, Valverde-Monge Marcela, Quirce Santiago, Caballero María L, Olaguibel José M, Del Pozo Victoria
Abstract excerpt
Clarifying inflammatory processes and categorising asthma into phenotypes and endotypes improves asthma management. Obesity worsens severe asthma and reduces quality of life, although its specific molecular impact remains unclear. We previously demonstrated that hsa-miR-26a-1-3p and hsa-miR-376a-3p, biomarkers related to an inflammatory profile, discriminate eosinophilic from non-eosinophilic asthmatics. We aimed...
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