Population structure and antimicrobial resistance patterns of Salmonella Typhi and Paratyphi A amid a phased municipal vaccination campaign in Navi Mumbai, India.

doi:10.1128/mbio.01179-23

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Population structure and antimicrobial resistance patterns of Salmonella Typhi and Paratyphi A amid a phased municipal vaccination campaign in Navi Mumbai, India.

mBio - 31 Aug 2023

da Silva Kesia Esther, Date Kashmira, Hirani Nilma, LeBoa Christopher, Jayaprasad Niniya, Borhade Priyanka, Warren Joshua, Shimpi Rahul, Hoffman Seth A, Mikoleit Matthew, Bhatnagar Pankaj, Cao Yanjia, Haldar Pradeep, Harvey Pauline, Zhang Chenhua, Daruwalla Savita, Dharmapalan Dhanya, Gavhane Jeetendra, Joshi Shrikrishna, Rai Rajesh, Rathod Varsha, Shetty Keertana, Warrier Divyalatha S, Yadav Shalini, Chakraborty Debjit, Bahl Sunil, Katkar Arun, Kunwar Abhishek, Yewale Vijay, Dutta Shanta, Luby Stephen P, Andrews Jason R

Abstract excerpt

We performed whole-genome sequencing of 174 Salmonella Typhi and 54 Salmonella Paratyphi A isolates collected through prospective surveillance in the context of a phased typhoid conjugate vaccine introduction in Navi Mumbai, India. We investigate the temporal and geographical patterns of emergence and spread of antimicrobial resistance. We evaluated the relationship between the spatial distance between households...

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PMID: 37504577
DOI: 10.1128/mbio.01179-23
PMCID: PMC10470601

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