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Ubiquitination of acetyltransferase Gcn5 contributes to fungal virulence in Fusarium graminearum

28 Jul 2023

Abstract excerpt

ABSTRACT The histone acetyltransferase general control non-depressible 5 (Gcn5) plays a critical role in the epigenetic landscape and chromatin modification for regulating a wide variety of biological events. However, the post-translational regulation of Gcn5 itself is poorly understood. Here, we found that Gcn5 was ubiquitinated and deubiquitinated by E3 ligase Tom1 and deubiquitinating enzyme Ubp14,...

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PMID: 37504517
DOI: 10.1128/mbio.01499-23

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