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Article

Association of gut microbiome with risk of intracranial aneurysm: a mendelian randomization study.

BMC neurology - 15 Jul 2023

Ma Chencheng, Zhang Weiwei, Mao Lei, Zhang Guangjian, Shen Yuqi, Chang Hanxiao, Xu Xiupeng, Jin Huiru, Li Zheng, Lu Hua

Abstract excerpt

OBJECTIVE: To investigate the potential causal link between genetic variants associated with gut microbiome and risk of intracranial aneurysm (IA) using two-sample mendelian randomization (MR). METHODS: We performed two sets of MR analyses. At first, we selected the genome-wide statistical significant(P < 5 × 10-8) single nucleotide polymorphisms (SNPs) as instrumental variables (IVs). Then, we selected the...

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Identifiers

PMID: 37454067
DOI: 10.1186/s12883-023-03288-2
PMCID: PMC10349504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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