Article
Newly Established Genetic System for Functional Analysis of MetSV.
International journal of molecular sciences - 6 Jul 2023
Gehlert Finn O, Weidenbach Katrin, Barüske Brian, Hallack Daniela, Repnik Urska, Schmitz Ruth A
Abstract excerpt
The linear chromosome of the Methanosarcina spherical virus with 10,567 bp exhibits 22 ORFs with mostly unknown functions. Annotation using common tools and databases predicted functions for a few genes like the type B DNA polymerase (MetSVORF07) or the small (MetSVORF15) and major (MetSVORF16) capsid proteins. For verification of assigned functions of additional ORFs, biochemical or genetic approaches were found...
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