Article
MALAT1 modulates trophoblast phenotype via miR-101-3p/VEGFA axis.
Archives of biochemistry and biophysics - 1 Aug 2023
Li Qin, Li Shuo, Ding Jin, Pang Bo, Li Ranran, Cao Hui, Ling Li
Abstract excerpt
Preeclampsia is a potentially life-threatening condition that can arise due to poor placentation and consequent abnormal uterine spiral artery remodeling. Abnormal placentation, in turn, is associated with aberrant trophoblast cell proliferation and apoptosis. Here, we investigated the lncRNA MALAT1 in trophoblast proliferation during early-onset preeclampsia (ePE). MALAT1 levels were examined in placental tissue...
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