Association between gut microbiota and primary ovarian insufficiency: a bidirectional two-sample Mendelian randomization study

Abstract excerpt

Background: Recent studies have indicated a potential correlation between intestinal bacteria and primary ovarian insufficiency (POI). However, the causal relationship between the gut microbiota (GM) and POI remains unclear. Methods: A bidirectional two-sample Mendelian randomization (MR) study was conducted to investigate the relationship between the GM and POI. Data on the GM were based on the MiBioGen...

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