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Article

Heart failure in patients is associated with downregulation of mitochondrial quality control genes

4 Jul 2023

Abstract excerpt

BACKGROUND: Mitochondrial dysfunction is one of key factors causing heart failure. We performed a comprehensive analysis of expression of mitochondrial quality control (MQC) genes in heart failure. METHODS: Myocardial samples were obtained from patients with ischemic and dilated cardiomyopathy in a terminal stage of heart failure and donors without heart disease. Using quantitative real-time PCR, we analysed a...

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PMID: 37403271
DOI: 10.1111/eci.14054

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