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Identification and analysis of mitochondria-related key genes of heart failure

7 Sept 2022

Abstract excerpt

Mitochondria-induced cell death is a vital mechanism of heart failure (HF). Thus, identification of mitochondria-related genes (Mito-RGs) based on transcriptome sequencing data of HF might provide novel diagnostic markers and therapeutic targets for HF. First, bioinformatics analysis was conducted on the GSE57338, GSE76701, GSE136547, and GSE77399 datasets in the Gene Expression Omnibus. Next, we analyzed HF-Mito...

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PMID: 36071497
DOI: 10.1186/s12967-022-03605-2

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