Article
Identification of integrase inhibitor-related drug resistance mutations in newly diagnosed ART-naïve HIV patients.
Microbial pathogenesis - 1 Aug 2023
Wang Nan, Xiong Xia, Liu Zhiqi, Zhang Ruixian, Luo Sha, Zhang Hongying, Wu Xuping
Abstract excerpt
BACKGROUND: In China, the recommended treatment regimens for HIV-infected individuals were tenofovir in combination with lamivudine or emtricitabine as NRTIs, efavirenz or rilpivirine as NNRTIs, lopinavir/ritonavir as protease inhibitors, and raltegravir or dolutegravir as INSTIs. The development of drug resistance increases the risk of viral rebound, opportunistic infections, and ultimately treatment failure...
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