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Comprehensive analysis of diabetic nephropathy expression profile based on weighted gene co-expression network analysis algorithm

2 Jul 2021

Abstract excerpt

BACKGROUND: Diabetic nephropathy (DN) is the major complication of diabetes mellitus, and leading cause of end-stage renal disease. The underlying molecular mechanism of DN is not yet completely clear. The aim of this study was to analyze a DN microarray dataset using weighted gene co-expression network analysis (WGCNA) algorithm for better understanding of DN pathogenesis and exploring key genes in the disease...

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PMID: 34215202
DOI: 10.1186/s12882-021-02447-2

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