The Impact of Long-Term Macrolide Exposure on the Gut Microbiome and Its Implications for Metabolic Control

Abstract excerpt

Long-term macrolide therapy is widely used in chronic respiratory diseases although its antibacterial activity can also affect the gut microbiota, a key regulator of host physiology. Macrolide-associated studies on the gut microbiota have been limited to short antibiotic courses and have not examined its consequences for host immune and metabolic regulation. This study revealed that long-term macrolides depleted...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Clostridium difficile and Clostridium perfringens research
• Share to Gastrointestinal motility and disorders
• Share to Gut microbiota and health