Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal relationship between gastro-esophageal reflux disease and risk of lung cancer: insights from multivariable Mendelian randomization and mediation analysis.

International journal of epidemiology - 5 Oct 2023

Liu Yi, Lai Hongjin, Zhang Ren, Xia Liang, Liu Lunxu

Abstract excerpt

AIM: A recent study has reported that anti-reflux surgery reduced the risk of lung cancer. However, the exact causal association between gastro-esophageal reflux disease (GORD) and lung cancer remains obscure. Therefore, we conducted a multivariable and network Mendelian randomization (MR) study to explore this potential association and mediation effect. METHODS: Independent single nucleotide polymorphisms (SNPs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma of Lung
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Gastroesophageal Reflux

Share to Genome-Wide Association Study

Share to Lung Neoplasms

Share to Mediation Analysis

Share to Mendelian Randomization Analysis

Source

Identifiers

PMID: 37344162
DOI: 10.1093/ije/dyad090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal relationship between gastro-esophageal reflux disease and risk of lung cancer: insights from multivariable Mendelian randomization and mediation analysis.PMID 37344162Read ↗

Causal associations between gastroesophageal reflux disease and lung cancer risk: A Mendelian randomization study.Semantic proximity Read ↗

Assessing the genetic relationship between gastroesophageal reflux disease and chronic respiratory diseases: a mendelian randomization studySemantic proximity Read ↗

Assessing the genetic relationship between gastroesophageal reflux disease and chronic respiratory diseases: A Mendelian randomization studySemantic proximity Read ↗

Causal relationship between lung diseases and risk of esophageal cancer: insights from Mendelian randomization.Semantic proximity Read ↗

Deciphering the Risk of Developing Lung Cancer after the Diagnosis of Gastric Cancer with Genetic Evidence: A European and East Asian Populations-Based Mendelian Randomization Analysis.Semantic proximity Read ↗

Irritability and risk of lung cancer: a Mendelian randomization and mediation analysis.Semantic proximity Read ↗

Unraveling the causality between gastroesophageal reflux disease and increased cancer risk: evidence from the UK Biobank and GWAS consortia.Semantic proximity Read ↗

Gastroesophageal reflux disease and the risk of respiratory diseases: a Mendelian randomization studySemantic proximity Read ↗

Causal analysis of the association between gastroesophageal reflux disease and idiopathic pulmonary fibrosisSemantic proximity Read ↗

The Causal Relationship Between Gastroesophageal Reflux Disease and Chronic Obstructive Pulmonary Disease: A Bidirectional Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

A two-sample Mendelian randomization study of the causal relationship between respiratory diseases, gastric cancer risk, and Helicobacter pylori infection.Semantic proximity Read ↗

Causal analysis of gastroesophageal reflux disease and esophageal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.