Article
Intracranial Efficacy of Adagrasib in Patients From the KRYSTAL-1 Trial With KRASG12C-Mutated Non-Small-Cell Lung Cancer Who Have Untreated CNS Metastases.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Oct 2023
Negrao Marcelo V, Spira Alexander I, Heist Rebecca S, Jänne Pasi A, Pacheco Jose M, Weiss Jared, Gadgeel Shirish M, Velastegui Karen, Yang Wenjing, Der-Torossian Hirak, Christensen James G, Sabari Joshua K
Abstract excerpt
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has already been...
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