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Article

CRISPR/Cas9-mediated simultaneous mutation of three salicylic acid 5-hydroxylase (OsS5H) genes confers broad-spectrum disease resistance in rice.

Plant biotechnology journal - 1 Sept 2023

Liu Xiong, Yu Yan, Yao Wei, Yin Zhongliang, Wang Yubo, Huang Zijian, Zhou Jie-Qiang, Liu Jinling, Lu Xuedan, Wang Feng, Zhang Guilian, Chen Guihua, Xiao Yunhua, Deng Huabing, Tang Wenbang

Abstract excerpt

Salicylic acid (SA) is an essential plant hormone that plays critical roles in basal defence and amplification of local immune responses and establishes resistance against various pathogens. However, the comprehensive knowledge of the salicylic acid 5-hydroxylase (S5H) in rice-pathogen interaction is still elusive. Here, we reported that three OsS5H homologues displayed salicylic acid 5-hydroxylase activity,...

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PMID: 37323119
DOI: 10.1111/pbi.14099
PMCID: PMC10440993

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