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Advancements of in vitro transcribed mRNA (IVT mRNA) to enable translation into the clinics

15 Jun 2023

Abstract excerpt

The accelerated progress and approval of two mRNA-based vaccines to address the SARS-CoV-2 virus were unprecedented. This record-setting feat was made possible through the solid foundation of research on in vitro transcribed mRNA (IVT mRNA) which could be utilized as a therapeutic modality. Through decades of thorough research to overcome barriers to implementation, mRNA-based vaccines or therapeutics offer many...

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PMID: 37321375
DOI: 10.1016/j.addr.2023.114961

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