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Establishment of a prognostic model for melanoma based on necroptosis-related genes.

Functional & integrative genomics - 14 Jun 2023

Sui Xiaohui, Zhang Xiaodan, Zhao Junde, Liu Jinxing, Li Shuling, Zhang Xiaowen, Wang Juntao

Abstract excerpt

In this study, the clinical implications and potential functions of necroptosis-related genes (NRGs) in melanoma were systematically characterized. A novel NRG signature was then constructed to analyze the immune status and prognosis of patients with melanoma. The NRG signatures for melanoma prognosis were searched using the Cancer Genome Atlas (TCGA) dataset and followed by stepwise Cox regression analysis....

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PMID: 37314547
DOI: 10.1007/s10142-023-01129-6

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