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Machine learning-based solution reveals cuproptosis features in inflammatory bowel disease

18 May 2023

Abstract excerpt

Background: Cuproptosis, a new cell death mode, is majorly modulated by mitochondrial metabolism and protein lipoylation. Nonetheless, cuproptosis-related genes (CRGs) have not yet been thoroughly studied for their clinical significance and relationship with the immune microenvironment in inflammatory bowel disease (IBD). Methods: We screened CRGs that had a significant correlation with immune status, which was...

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PMID: 37275904
DOI: 10.3389/fimmu.2023.1136991

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